Stop Fighting Your Own Muscles: Restore Control and Comfort.

When your muscles turn against you, our multi-layered approach relaxes tension, reduces inflammation, and prevents future spasms.

Camphor

Releases deep muscle knots that feel like steel cables.

When muscles lock up into those painful knots you can actually feel under your skin, camphor's penetrating warmth helps break through that rigid tension. Perfect for those trigger points that make you wince when touched.

Breaks through deep muscle knots and trigger points.
Increases blood flow to chronically tight muscle tissue.
Ideal for muscle tension that feels hard and unyielding.

"Camphor remains one of my go-to ingredients for patients with chronic muscle tension. It creates this beautiful warming sensation that actually improves circulation to knotted muscle fibers. Patients tell me it's like their muscles finally remember how to let go."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Menthol

Cools the fire of acute muscle spasms instantly.

When a muscle spasm hits like lightning—whether it's your calf at night or your back during the day—menthol provides immediate cooling relief that overrides those sharp spasm signals while other ingredients work to relax the muscle.

Instant cooling relief for sudden muscle spasms.
Perfect for acute pain that takes your breath away.
Works fast when muscles seize up unexpectedly.

"What I love about menthol is how fast it works. Within minutes, it's activating those cold receptors and essentially telling the brain 'pay attention to this cooling sensation, not that muscle spasm.' It's immediate relief while the other ingredients do their deeper muscle work."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Lidocaine

Silences the sharp nerve pain that comes with muscle tension.

Muscle spasms often irritate nearby nerves, creating sharp, electric pain on top of the muscle tension. Lidocaine quiets those hypersensitive nerves so you can focus on healing, not hurting.

Blocks sharp nerve pain that accompanies muscle spasms.
Helps when muscle tension creates radiating pain.
Especially effective for neck, shoulder, and back spasms.

"Lidocaine is a game changer for patients whose muscle tension has that sharp, electric component. I can titrate the concentration based on how irritated those nerves have become from chronic muscle tension. It's like having a volume control for the pain that lets them focus on relaxation."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

NSAIDs (Diclofenac, Ibuprofen, Ketoprofen)

Targets muscle inflammation that perpetuates spasm cycles.

The inflammation around chronically tight muscles gets direct treatment with prescription strength anti-inflammatories. All the power of oral medications without the stomach upset that adds stress to your already tense body.

Prescription strength inflammation control for muscle tissue.
Reduces swelling that keeps muscles in spasm.
No stomach irritation or drowsiness like oral muscle relaxers.

"This is where topical really shines for muscle tension. I can give patients the same anti-inflammatory power they'd get from oral NSAIDs, but delivered right to the inflamed muscle tissue. Less than 6% goes systemic, which means virtually no side effects that could interfere with their daily activities."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Amitriptyline

Calms nerves that chronic muscle tension has hypersensitized.

Months or years of muscle tension change how your nervous system processes pain signals. Your muscles start spasming with minimal provocation. Amitriptyline helps reset that hypersensitivity so normal activities don't trigger spasms.

Reduces constant background muscle tension and achiness.
Helps with muscle pain that never fully goes away.
Especially effective for chronic neck, shoulder, and back tension.

"Chronic muscle tension changes how nerves process signals. Amitriptyline helps reset that hypersensitivity. I use it especially for patients who say their muscles feel tight even when they're trying to relax. It addresses the nerve component that develops with long-term muscle problems."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Baclofen

The master muscle relaxer that helps locked muscles finally let go.

When muscles are stuck in chronic contraction, they need help remembering how to relax. Baclofen works directly on muscle fibers to break the spasm cycle and restore normal muscle tone.

Directly relaxes muscle fibers stuck in chronic contraction.
Breaks the spasm-tension-more spasm cycle.
Helps muscles return to their normal, relaxed state.

"Baclofen is the gold standard for muscle relaxation. Unlike oral muscle relaxers that make the whole body drowsy, topical baclofen works exactly where you need it. Patients tell me their muscles finally feel like they can breathe again."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Cyclobenzaprine

Stops protective muscle guarding that creates more tension.

When one muscle hurts, surrounding muscles automatically tense up to protect it. This creates a cascade of tension that spreads throughout your body. Cyclobenzaprine interrupts that protective pattern.

Prevents protective muscle guarding around problem areas.
Stops tension from spreading to surrounding muscles.
Helps your body move naturally without unconscious bracing.

"I see this all the time—patients who develop protective muscle tension around one problem area, and it spreads like wildfire. Cyclobenzaprine interrupts that pattern. Patients tell me they didn't realize how much of their body was participating in the tension until it stopped."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Transdermal Pain Cream Base

Delivers relief deep into muscle fibers where tension lives.

Muscle spasms and chronic tension exist deep within muscle tissue where regular creams can't reach. Our pharmacist developed base carries active ingredients through multiple tissue layers to reach the actual muscle fibers causing your pain.

Penetrates to deep muscle fibers where spasms originate.
Sustained release provides hours of muscle relaxation.
Specifically designed for deep muscle tissue delivery.

"The base is everything for muscle relief. You can have the best muscle relaxants in the world, but if your base can't carry them through the skin barrier and into the deep muscle tissue, you're just expensive moisturizer. Our transdermal system is specifically designed for penetrating to where muscle tension actually lives."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Muscle Relief That Moves with You. Not Against You.

Whether it's sudden muscle spasms, chronic muscle tension, or stubborn muscle strains, our prescription-strength ingredients target the root cause not just the surface.

Stop Muscle Spasms in Their Tracks

Fast acting muscle relaxants calm those sudden muscle spasms that hijack your day. Whether it's your back seizing up or your calf cramping mid-sleep.

No Drowsiness, No Fog.

Unlike oral muscle relaxants that knock you out, our topical formula helps tight muscles and muscle spasms let go while keeping your mind sharp and focused.

Targets muscle strains and spasms at the source.

Goes deeper than surface pain, Twinge Health helps calm overactive nerves and release locked muscle fibers where muscle spasms actually start.

Break the muscle tension cycle.

From stress-tightened shoulders to chronic muscle strain patterns, we target both the nerve signals and muscle fibers that keep you locked up.

Works around your life.

Apply before bed for muscle cramp free sleep, after workouts for faster muscle recovery, or during the day for ongoing muscle strain and spasm relief non-greasy and fast-absorbing.

Built by experts.
Backed by real access.

Pharmacist-formulated. Doctor-approved. And you can message a real expert anytime.

They Called It a Game Changer. We Call It Personalized Muscle Relief.

These reviews come from people who thought they'd tried everything for their muscle strains and spasms. Until they tried something made for their muscle pain.

Jordan

Electrician, 31

My go to for muscle pulls and tightness

I strained my calf last month. Twinge reduced the soreness and helped me bounce back faster.

Camille, 44

Pilates Instructor

Calms spasms without that menthol overload

I get mid-back spasms weekly. Twinge soothes the muscle without that overpowering medicinal smell.

Greg, 56

Bus Driver

Took care of my lower back spasms

Sitting all day triggered awful back spasms. After a week with Twinge, I could move normally again.

Keisha, 39

Massage Therapist

I recommend it

This cream can help with muscle knots. Twinge eases flare-ups better than most pro products.

Dylan, 28

EMT

Works fast on sudden muscle cramps

My quads seize up after long shifts. A little Twinge and the cramping dies down quickly.

Marcy, 53

Office Manager

Helps when my neck muscles lock up

I get stress-related neck spasms. This cream loosens the tension in under 20 minutes. Lifesaver.

Ahmed, 47

Taxi Driver

Loosened tight muscles

My upper back was locked for weeks. Twinge softened the knots and brought mobility back.

Sienna, 34

Store Manager

Best thing I've used for muscle tightness

Long hours and heavy lifting leave me stiff. Twinge relieves the ache without making my skin greasy.

Linda, 50

Mom

No more middle-of-the-night leg spasms

I'd wake up with severe leg cramps. I started using Twinge and they're practically gone.

Frequently Asked Questions About Custom Muscle Strain and Spasm Relief Creams.

From safety to shipping, here's everything you need to know about getting prescription-strength muscle strain and spasm relief cream delivered right to your door.

See How Twinge Compares to Your Current Pain Relief Regimen.

From appointments to disappointments, you've paid the price for pain relief that didn't deliver. Twinge is one cream that finally does.

OTC Creams

Rx Oral Pills

Twinge Cream

🛒 Access

Grab off the shelf and hope it helps.

Doctor visits, insurance hassle, and pharmacy pickup.

Quick telehealth visit with a doctor, shipped fast to your door.

⏱️ Time to Relief

Immediate if it's in stock.

Wait in line or wait for it to kick in.

Order from home and ships in two days with USPS Priority.

🧬 Personalization

Same formula for everyone.

One-size dose based on averages.

Tailored to your pain type, area, and history.

💪 Strength & Potency

Capped by over‑the‑counter limits.

Prescription strength, fixed dose.

Prescription strength, calibrated to your body needs.

😟 Side Effects

Can irritate your skin.

Risk of nausea, GI issues, liver/kidney strain, addiction.

Low systemic impact. No habit forming ingredients.

🎯 Targeting

Masks surface symptoms.

Distributes through your entire body.

Pain cream base penetrates deep into the skin to deliver powerful active ingredients right where it hurts.

⏳ Duration

Fades fast, needs reapplying often.

Wears off unevenly, leaves you chasing the next dose.

Stays active longer so you get through the day.

💰 Total Cost

$10 to $40 per tube.

$30 to $200 per month after copays and deductibles.

$79 / month

Includes custom cream, physician consult & shipping.

Questions? Chat with us

One Cream. One Price. Zero Nonsense.

From appointments to disappointments, you've paid the price for pain relief that didn't deliver. Twinge is one cream that finally does.

🛒 Access

⏱️ Time to Relief

🧬 Personalization

⚡ Strength & Potency

⚠️ Side Effects

🎯 Targeting

⏳ Duration

💰 Total Cost

OTC Creams:

$10 to $40 per tube.
Oral Pills:

$30 to $200 per month after copays and deductibles.
Twinge Custom Cream:

$79 all in — custom cream, physician consult, fast shipping.

$79/month supply. No copays. No insurance. No hidden fees.

Arthritis & Joint Pain

Back Pain

Neuropathy

Foot & Heel Pain

Muscle Spasms & Strains

Sports & Overuse Injuries

Ready for Real Relief?

⌛ Limited Spots Remaining for September

Is Twinge Right for Your Pain?

Trusted by hundreds for lasting pain relief

Get Custom Muscle Spasm Relief That Breaks the Pain Cycle.

Stop letting muscle spasms and strains control your day and night. Get a prescription strength formula specifically designed for your muscle pain delivered to your door for one flat price.With Twinge Health muscle strain and spasm relief is simple. Here's what you get:

Real doctor reviews your muscle strain and spasm patterns and prescribes your formula.

Targeted ingredients for muscle strains and spasms. Not generic relaxation.

Skip pharmacy run. Your muscle relief cream ships free and fast with 2 day USPS Priority mail.

Your Muscles Betray You at the Worst Possible Moments.

Get Doctor Prescribed Muscle Strain & Spasm Relief Without the Wait.

Skip the waiting rooms and sleepless nights. Get personalized, prescription strength muscle strain and spasm treatment delivered straight to your door.

Map your muscle pain.

Your custom cream is made.

Your relief gets delivered.

Stop Fighting Your Own Muscles: Restore Control and Comfort.

When your muscles turn against you, our multi-layered approach relaxes tension, reduces inflammation, and prevents future spasms.

Releases deep muscle knots that feel like steel cables.

Dr. Javed

Cools the fire of acute muscle spasms instantly.

Dr. Javed

Silences the sharp nerve pain that comes with muscle tension.

Dr. Javed

Targets muscle inflammation that perpetuates spasm cycles.

Dr. Javed

Calms nerves that chronic muscle tension has hypersensitized.

Dr. Javed

The master muscle relaxer that helps locked muscles finally let go.

Dr. Javed

Stops protective muscle guarding that creates more tension.

Dr. Javed

Delivers relief deep into muscle fibers where tension lives.

Dr. Javed

Muscle Relief That Moves with You. Not Against You.

Whether it's sudden muscle spasms, chronic muscle tension, or stubborn muscle strains, our prescription-strength ingredients target the root cause not just the surface.

Stop Muscle Spasms in Their Tracks

No Drowsiness, No Fog.

Targets muscle strains and spasms at the source.

Break the muscle tension cycle.

Works around your life.

Built by experts. Backed by real access.

They Called It a Game Changer. We Call It Personalized Muscle Relief.

These reviews come from people who thought they'd tried everything for their muscle strains and spasms. Until they tried something made for their muscle pain.

Jordan

My go to for muscle pulls and tightness

Camille, 44

Calms spasms without that menthol overload

Greg, 56

Took care of my lower back spasms

Keisha, 39

I recommend it

Dylan, 28

Works fast on sudden muscle cramps

Marcy, 53

Helps when my neck muscles lock up

Ahmed, 47

Loosened tight muscles

Sienna, 34

Best thing I've used for muscle tightness

Linda, 50

No more middle-of-the-night leg spasms

Frequently Asked Questions About Custom Muscle Strain and Spasm Relief Creams.

From safety to shipping, here's everything you need to know about getting prescription-strength muscle strain and spasm relief cream delivered right to your door.

How is Twinge different from OTC muscle creams?

Do I need a prescription for Twinge muscle spasm cream?

What types of muscle problems does Twinge help with?

Is Twinge covered by insurance?

Is it safe to use Twinge cream long term for muscle problems?

Can I use Twinge cream with my current muscle medications?

What if I'm allergic to certain ingredients?

Can I use Twinge cream with massage therapy or physical therapy?

How quickly do I see muscle improvements with Twinge?

What if the cream doesn't work for my muscle problems?

What if my muscle problems change or move to different areas?

Stop letting muscle spasms and strains control your day and night. Get a prescription strength formula specifically designed for your muscle pain delivered to your door for one flat price.

With Twinge Health muscle strain and spasm relief is simple. Here's what you get:

Built by experts.
Backed by real access.