Every Ingredient Has One Job: Get Your Joints Moving Again.

We don't add fillers or fancy fragrances. Every component targets a specific part of your arthritis pain.

Camphor

Relieves stubborn morning stiffness and arthritic aching.

When arthritis makes your joints feel locked up or your muscles tense around inflamed areas, camphor delivers a penetrating warmth that releases that trapped tension. Perfect for those mornings when your body feels like it aged 20 years overnight.

Breaks through morning joint stiffness that lasts for hours.
Improves blood flow to cartilage and surrounding tissue.
Ideal for arthritis pain that feels deep and heavy.

“Camphor is one of my go-to ingredients for arthritis patients. It creates this beautiful warming sensation that actually improves circulation to the joint capsule. Patients tell me it’s like their joints finally get to breathe again.”

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Menthol

Cools the fire of arthritis flares instantly.

When your joints feel like they're burning from the inside out, menthol provides immediate cooling relief. It's especially powerful during those sudden flares when your arthritis goes from manageable to unbearable in minutes.

Instant cooling relief for inflamed, angry joints.
Perfect for breakthrough arthritis pain during flares.
Works fast when pain spikes unexpectedly.

"I love how fast menthol works. Within minutes, it's activating those cold receptors and essentially telling the brain 'pay attention to this cooling sensation, not that joint pain.' It's an immediate relief while the other ingredients do their deeper work."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Lidocaine

Silences the sharp, electric pain of nerve irritation.

Arthritis doesn't just damage cartilage, it irritates nerves around joints, creating that sharp, shooting pain that feels like electricity. Lidocaine quiets those hypersensitive nerves so you can move without wincing.

Blocks sharp, shooting nerve pain around arthritic joints.
Helps with sleep disruption from nighttime joint pain.
Especially effective for hands, wrists, and finger joints.

"Lidocaine is a game changer for patients whose arthritis has that electric, burning quality. We can adjust the concentration based on how sensitive their nerves have become. It's like having a volume control for pain signals."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

NSAIDs (Diclofenac, Ibuprofen, Ketoprofen)

Attacks arthritis inflammation right at the source.

The gold standard for arthritis treatment has been prescription strength anti-inflammatories that target swollen joint tissue directly. Get all the inflammation fighting power of oral medications without destroying your stomach or stressing your heart.

Prescription strength inflammation control for arthritic joints.
Reduces morning stiffness and joint swelling.
No stomach bleeding or cardiovascular risks like oral NSAIDs.

"This is where topical pain relief really shines. I can give patients the same anti-inflammatory power they'd get from oral NSAIDs, but delivered right to the inflamed tissue. Less than 6% goes systemic, which means no GI or cardiovascular risk. It's the best of both worlds."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Amitriptyline

Calms nerves that arthritis has made hypersensitive.

Years of arthritis change how your nervous system processes pain. Joints start hurting even when you're not using them. Amitriptyline helps reset that hypersensitivity so your joints only hurt when they actually should.

Reduces constant background ache in arthritic joints.
Helps with arthritis pain that persists even at rest.
Especially effective for rheumatoid and psoriatic arthritis.

"Chronic pain changes how nerves process signals. Amitriptyline helps reset that hypersensitivity. I use it especially for patients who say their joints hurt even when they're not moving. It addresses the nerve component that develops with long term arthritis."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Baclofen

Relaxes muscles that guard and protect arthritic joints.

When joints hurt, the muscles around them automatically tense up for protection. This creates a vicious cycle where muscles tighten which makes stiff joints even stiffer. Baclofen breaks that cycle by helping protective muscles finally relax.

Releases muscle tension that compounds joint stiffness.
Improves range of motion in arthritic joints.
Reduces the "guarding" that makes arthritis worse.

"Patients don't realize how much their muscles guard around arthritic joints. That protective tension actually makes everything worse. Baclofen breaks that cycle by relaxing the muscles so the joint can move more freely."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Cyclobenzaprine

Prevents muscle spasms that arthritis triggers.

Arthritis pain often causes sudden muscle spasms as your body tries to protect damaged joints. These spasms become their own source of agony. Cyclobenzaprine stops that protective spasm response before it spirals out of control.

Prevents muscle spasms around inflamed joints.
Breaks the pain-spasm-pain cycle common in arthritis.
Helps you move naturally without unconscious bracing.

"I see this all the time: Arthritis patients who develop these protective muscle spasms that become their own source of pain. Cyclobenzaprine interrupts that pattern. Patients tell me they didn't even realize how much they were tensing up until they stopped."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Transdermal Pain Cream Base

Delivers relief deep into arthritic joint tissue.

Arthritis pain lives deep inside joint spaces where regular creams can't reach. Our hypoallergenic pain cream base carries active ingredients through skin, muscle, and connective tissue to reach the actual source of your arthritis pain.

Penetrates to joint capsules where arthritis inflammation occurs.
Sustained release provides hours of relief per application.
Specifically designed for deep joint and cartilage delivery.

"The base is everything. You can have the best active ingredients in the world, but if your base can't carry them through the skin barrier and into the joint space, you have an expensive moisturizer. Our transdermal pain cream base is specifically designed for deep penetration and sustained release for lasting relief."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Built to Move Joints Again.
Not Just Mask Pain.

Twinge Health is designed for arthritis patients. Every element, from prescription-strength ingredients to arthritis friendly applicator, works to reduce inflammation, ease stiffness, and give your joints the freedom to move again.

Get the exact dose, every time

Twist, click, apply. No waste. No second-guessing.

Relief without the stomach pain.

Get targeted healing, not whole-body side effects. Feel powerful anti-inflammatory action delivered directly to your joints without the GI bleeding, kidney damage, or heart risks that traditional pills come with.

When morning stiffness locks you up...

We help you move again. Prescription anti-inflammatories and muscle relaxants work overnight to reduce the stiffness that affects millions of arthritis patients for over an hour each morning.

For the grip strength you thought was gone forever.

Custom concentrations target the small joints that control everything you do. Open jars again. Button shirts without help. Hold your grandkids without wincing.

Safe for daily use, strong enough to work.

Prescription potency without prescription risks. Formulated for long-term arthritis management without compromising your safety or requiring constant doctor visits.

Built by experts.
Backed by real access.

Pharmacist-formulated. Doctor-approved. And you can message a real expert anytime.

They Called It a Game Changer. We Call It Personalized Relief.

These reviews come from people who thought they'd tried everything. Until they tried something made for their pain.

Tina

Retired Teacher, 63

Got my mornings back

Mornings used to be the worst. I'd sit on the edge of the bed just trying to will my knees to bend. This cream gave me my mornings back.

Carlos, 59

Auto Technician

Small miracle for my hands

I tried everything for my stiff hands. Within a few days of using this, I could open jars again without wincing. It felt like a small miracle.

Janice, 46

Data Analyst

No more stack of pain meds needed

The swelling in my wrists made typing unbearable. Now I can get through a workday without reaching for pain meds.

Leroy, 71

Veteran

Walking downstairs is easier!

I used to dread walking downstairs. The ache in my knees was awful. Since using this cream, it's been so much easier to move.

Miriam, 68

Home Gardener

Back to my favorite hobby

Arthritis made gardening painful. This took the edge off enough that I got back to my favorite hobby without needing to push through pain.

Robert, 65

Retired Carpenter

Can play with grandkids again!

My hip pain was keeping me from playing with my grandkids. This cream lets me get down on the floor and back up without agony.

Patricia, 58

Nurse

Sleep through the night!

My shoulder pain used to wake me up constantly. Now I can sleep through the night and wake up feeling refreshed.

Michael, 62

Sales Representative

Can drive without pain!

My back pain made driving unbearable. This cream lets me sit comfortably for long drives to visit family.

Sandra, 55

Administrative Assistant

Back to daily walks!

My ankle arthritis was keeping me from my daily walks. This cream has me back on the trails and feeling mobile again.

Frequently Asked Questions About Custom Arthritis Pain Relief Cream.

From safety to shipping, here's everything you need to know about getting prescription-strength arthritis cream made specifically for your joints—delivered right to your door.

See How Twinge Compares to Your Current Pain Relief Regimen.

From appointments to disappointments, you've paid the price for pain relief that didn't deliver. Twinge is one cream that finally does.

OTC Creams

Rx Oral Pills

Twinge Cream

🛒 Access

Grab off the shelf and hope it helps.

Doctor visits, insurance hassle, and pharmacy pickup.

Quick telehealth visit with a doctor, shipped fast to your door.

⏱️ Time to Relief

Immediate if it's in stock.

Wait in line or wait for it to kick in.

Order from home and ships in two days with USPS Priority.

🧬 Personalization

Same formula for everyone.

One-size dose based on averages.

Tailored to your pain type, area, and history.

💪 Strength & Potency

Capped by over‑the‑counter limits.

Prescription strength, fixed dose.

Prescription strength, calibrated to your body needs.

😟 Side Effects

Can irritate your skin.

Risk of nausea, GI issues, liver/kidney strain, addiction.

Low systemic impact. No habit forming ingredients.

🎯 Targeting

Masks surface symptoms.

Distributes through your entire body.

Pain cream base penetrates deep into the skin to deliver powerful active ingredients right where it hurts.

⏳ Duration

Fades fast, needs reapplying often.

Wears off unevenly, leaves you chasing the next dose.

Stays active longer so you get through the day.

💰 Total Cost

$10 to $40 per tube.

$30 to $200 per month after copays and deductibles.

$79 / month

Includes custom cream, physician consult & shipping.

Questions? Chat with us

One Cream. One Price. Zero Nonsense.

From appointments to disappointments, you've paid the price for pain relief that didn't deliver. Twinge is one cream that finally does.

🛒 Access

⏱️ Time to Relief

🧬 Personalization

⚡ Strength & Potency

⚠️ Side Effects

🎯 Targeting

⏳ Duration

💰 Total Cost

OTC Creams:

$10 to $40 per tube.
Oral Pills:

$30 to $200 per month after copays and deductibles.
Twinge Custom Cream:

$79 all in — custom cream, physician consult, fast shipping.

$79/month supply. No copays. No insurance. No hidden fees.

Arthritis & Joint Pain

Back Pain

Neuropathy

Foot & Heel Pain

Muscle Spasms & Strains

Sports & Overuse Injuries

Ready for Real Relief?

⌛ Limited Spots Remaining for September

Is Twinge Right for Your Pain?

Trusted by hundreds for lasting pain relief

Custom Made Arthritis Relief That Actually Works for Your Joints.

Stop settling for generic pain creams that barely touch the surface. Get a prescription strength relief formula specifically made for your arthritis, not a one size fits all cream.With Twinge Health pain relief is simple. Here's what you get:

Pain relief formula designed by a Pharmacist.

Licensed physician prescribes hand picked ingredients for your joints.

Get pain relief delievered with free 2 day shipping.

Every Morning Feels Like Starting the Day in Slow Motion.

Get Doctor Prescribed Arthritis Relief Without Leaving Home.

Skip the waiting rooms and pharmacy runs. Get personalized, prescription strength arthritis treatment delivered straight to your door.

Complete your arthritis assessment online.

Your custom formula is created.

Relief delivered to your door, freedom in your hands.

Every Ingredient Has One Job: Get Your Joints Moving Again.

We don't add fillers or fancy fragrances. Every component targets a specific part of your arthritis pain.

Relieves stubborn morning stiffness and arthritic aching.

Cools the fire of arthritis flares instantly.

Silences the sharp, electric pain of nerve irritation.

Attacks arthritis inflammation right at the source.

Calms nerves that arthritis has made hypersensitive.

Relaxes muscles that guard and protect arthritic joints.

Prevents muscle spasms that arthritis triggers.

Delivers relief deep into arthritic joint tissue.

Built to Move Joints Again. Not Just Mask Pain.

Twinge Health is designed for arthritis patients. Every element, from prescription-strength ingredients to arthritis friendly applicator, works to reduce inflammation, ease stiffness, and give your joints the freedom to move again.

Get the exact dose, every time

Relief without the stomach pain.

When morning stiffness locks you up...

For the grip strength you thought was gone forever.

Safe for daily use, strong enough to work.

Built by experts. Backed by real access.

They Called It a Game Changer. We Call It Personalized Relief.

These reviews come from people who thought they'd tried everything. Until they tried something made for their pain.

Tina

Got my mornings back

Carlos, 59

Small miracle for my hands

Janice, 46

No more stack of pain meds needed

Leroy, 71

Walking downstairs is easier!

Miriam, 68

Back to my favorite hobby

Robert, 65

Can play with grandkids again!

Patricia, 58

Sleep through the night!

Michael, 62

Can drive without pain!

Sandra, 55

Back to daily walks!

Frequently Asked Questions About Custom Arthritis Pain Relief Cream.

From safety to shipping, here's everything you need to know about getting prescription-strength arthritis cream made specifically for your joints—delivered right to your door.

How is this different from creams I can buy at the store?

Is telehealth arthritis treatment legal?

Do I need insurance? Is this covered by HSA/FSA?

Is it safe to use topical arthritis cream long-term?

Can I use this with my other arthritis medications?

What if I have sensitive skin?

Are there any side effects I should watch for?

How quickly will I notice improvement in my arthritis pain?

Will this work for my specific type of arthritis?

What if it doesn't work for me?

How does this compare to steroid injections?

How much cream do I apply and how often?

Can I apply this to multiple joints?

Is it greasy or messy like other creams?

How do I store the cream?

How long does shipping take?

What if I need a refill?

Can I travel with this cream?

What if I move or change addresses?

Stop settling for generic pain creams that barely touch the surface. Get a prescription strength relief formula specifically made for your arthritis, not a one size fits all cream.

With Twinge Health pain relief is simple. Here's what you get:

Built to Move Joints Again.
Not Just Mask Pain.

Built by experts.
Backed by real access.