Every Ingredient Targets a Different Piece of Your Back Pain

We don't add fillers or fancy fragrances. Every component addresses a specific way back pain ruins your day.

Camphor

Relieves deep muscle tension that locks up your spine.

When your back muscles clench up to protect an injured area, camphor's penetrating warmth helps release that protective tension. Perfect for those days when your entire back feels like it's in a vice grip.

Breaks through deep muscle tension and spasms.
Improves blood flow to tight, overworked back muscles.
Ideal for back pain that feels rigid and locked up.

"Camphor is a go to ingredient for back pain patients. It creates this wonderful warming sensation that actually improves circulation to tight muscle fibers. Patients tell me it's like their back finally gets permission to relax."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Menthol

Cools the fire of acute back flares instantly.

Perfect for when your back goes from fine to excruciating in seconds from a small wrong move or lifting something. Menthol provides immediate cooling relief that overrides those sharp pain signals while other ingredients get to work.

Instant cooling relief for sudden back pain flares.
Perfect for breakthrough pain that stops you in your tracks.
Works fast when you've "thrown your back out."

"I love how quickly menthol works. Within minutes, it's activating those cold receptors and essentially telling the brain 'pay attention to this cooling sensation, not that back spasm.' It's an immediate relief while the other ingredients do their deeper work."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Lidocaine

Silences shooting nerve pain down your legs.

Back pain often involves pinched nerves that send shooting, electric pain down your legs. Lidocaine quiets those hypersensitive nerve pathways so you can move without that sharp, breath-taking pain.

Blocks sharp, shooting pain that radiates from your back.
Helps with sciatica and nerve pain down legs.
Especially effective for herniated disc pain.

"Lidocaine is a game changer for patients whose back pain has that electric, shooting quality down the leg. We adjust the concentration based on how irritated those nerve roots have become. It's like having a volume control for sciatica."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

NSAIDs (Diclofenac, Ibuprofen, Ketoprofen)

Targets spine inflammation that causes morning stiffness.

The inflammation around your spine that makes mornings miserable gets direct treatment with prescription strength anti-inflammatories. All the power of oral medications without destroying your stomach lining.

Prescription strength inflammation control for spinal joints.
Reduces morning back stiffness and pain.
No stomach bleeding or liver damage like oral NSAIDs.

"This is where topical pain relief creams really shine. I can give patients the same anti-inflammatory power they'd get from oral NSAIDs, but delivered right to the inflamed spinal tissue. Less than 6% goes systemic, which means no GI or cardiovascular risk. It's the best of both worlds."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Amitriptyline

Calms nerves that chronic back pain has sensitized.

Years of back pain change how your nervous system processes signals. Your back starts hurting even from gentle movements. Amitriptyline helps reset that hypersensitivity so normal activities don't trigger pain.

Reduces constant background ache in chronic back pain.
Helps with back pain that never fully goes away.
Especially effective for fibromyalgia-related back pain.

"Chronic pain changes how nerves process signals. Amitriptyline helps reset that hypersensitivity. We typically use it for patients who say their back hurts even when they are just sitting still. It addresses the nerve sensitization that develops with long term back problems."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Baclofen

Relaxes the muscle guarding that makes back pain worse.

When your back hurts, every muscle around your spine tenses up to protect it. This creates a painful cycle where muscle tension makes the original problem worse. Baclofen breaks that cycle.

Releases protective muscle tension around the spine.
Reduces muscle spasms that compound back injury.
Helps you move naturally without bracing.

"Patients don't realize how much their entire torso guards around a back injury. That protective tension actually makes everything worse. Baclofen breaks that cycle by relaxing the muscles so the spine can heal without being held rigid."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Cyclobenzaprine

Stops the spasm cycle that keeps you stuck.

Back injuries often trigger muscle spasms as your body tries to immobilize the area. These spasms become their own source of agony and prevent healing. Cyclobenzaprine interrupts that painful pattern.

Prevents muscle spasms that follow back injury.
Breaks the pain-spasm-more pain cycle.
Helps you move without triggering protective reflexes.

"I see a lot of back pain patients who develop these protective muscle spasms that become worse than the original injury. Cyclobenzaprine interrupts that pattern. Patients tell me they didn't even realize how much they were bracing until they stopped."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Transdermal Pain Cream Base

Delivers relief deep into spinal tissue where it's needed.

Back pain originates deep in your spine in discs, joints, and muscle layers that regular creams can't reach. Our hypoallergenic pain cream base carries active ingredients through multiple tissue layers to the actual source of your pain.

Penetrates to deep spinal muscles and joints.
Sustained release provides hours of relief per application.
Specifically designed for deep spine and muscle delivery.

"The base is everything. You can have the best active ingredients in the world, but if your base can't carry them through the skin barrier and into those deep paraspinal muscles, you have an expensive moisturizer. Our transdermal system is specifically designed for deep penetration to spinal tissue."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Not Another Patch or Pill. This Is Real Back Relief.

Twinge targets the muscles, nerves, and inflammation causing your back pain with prescription-strength ingredients that work where you hurt most.

Beat your back to the punch.

Your back pain is predictable, worst in the morning, better as you move. Our overnight formula flips the script so you start your day ahead of the pain curve.

Relief without the stomach pain.

Get targeted healing, not whole-body side effects. Feel the powerful anti-inflammatory and anti-spasmatic formula delivered directly to your back without the GI bleeding, kidney damage, or heart risks that traditional pills come with.

Twinge penetrates deep.
Inflammation retreats.
Muscles unlock.
You move freely.

Stops spasms before they stop you.

Get powerful muscle relaxants to prevent those sudden seize ups that drop you mid step. Move with confidence again whether you're lifting, bending, or just getting through your day

Built for your specific back pain.

Lower back stiffness? Sciatica shooting down your leg? Upper back knots? We compound your cream based on exactly where and how your back hurts not a one size fits all approach.

Built by experts.
Backed by real access.

Pharmacist-formulated. Doctor-approved. And you can message a real expert anytime.

They Called It a Game Changer. We Call It Personalized Relief.

These reviews come from people who thought they'd tried everything. Until they tried something made for their pain.

Matt

Physician, 52

Relieved my chronic lower back pain in days

As a doctor, I was skeptical, but Twinge really eased my lumbar pain fast without side effects.

Amanda, 45

Receptionist

I can sit all day without discomfort again

My back would ache by noon. Since using Twinge, workdays feel manageable again.

Jeff, 80

Retired

Helps me stay active and avoid the cane

My lower back stiffness made walking hard. Twinge gave me real relief within a week.

Theresa, 56

Accountant

Finally, something that actually targets the pain

I've tried everything for back spasms. This cream worked better than anything my doctor prescribed.

Paul, 52

Carpenter

Perfect for long days on the job site

After years of heavy lifting, my back was wrecked. Twinge made a noticeable difference fast.

LauraAnne, 59

Social Worker

Quick, easy relief for tension in my spine

Stress builds in my back by afternoon. Twinge is the only thing that calms it quickly.

Ani, 38

Web Developer

Soothing relief after long hours at my desk

Sitting all day caused daily backaches. I apply Twinge at night and wake up pain-free.

Derek, 60

General Manager

Works better than anything I've tried before

I've had recurring back issues for decades. This cream made a real difference after two uses.

Yao, 47

Engineer

Surprised by how well it worked for me

I expected mild relief, but my lower back pain almost vanished. Will definitely keep using it.

Frequently Asked Questions About Custom Back Pain Relief Creams.

From safety to shipping, here's everything you need to know about getting prescription-strength back pain cream made specifically for your spine and back muscles—delivered right to your door.

See How Twinge Compares to Your Current Pain Relief Regimen

From appointments to disappointments, you've paid the price for pain relief that didn't deliver. Twinge is one cream that finally does.

OTC Creams

Rx Oral Pills

Twinge Cream

🛒 Access

Grab off the shelf and hope it helps.

Doctor visits, insurance hassle, and pharmacy pickup.

Quick telehealth visit with a doctor, shipped fast to your door.

⏱️ Time to Relief

Immediate if it's in stock.

Wait in line or wait for it to kick in.

Order from home and ships in two days with USPS Priority.

🧬 Personalization

Same formula for everyone.

One-size dose based on averages.

Tailored to your pain type, area, and history.

💪 Strength & Potency

Capped by over‑the‑counter limits.

Prescription strength, fixed dose.

Prescription strength, calibrated to your body needs.

😟 Side Effects

Can irritate your skin.

Risk of nausea, GI issues, liver/kidney strain, addiction.

Low systemic impact. No habit forming ingredients.

🎯 Targeting

Masks surface symptoms.

Distributes through your entire body.

Pain cream base penetrates deep into the skin to deliver powerful active ingredients right where it hurts.

⏳ Duration

Fades fast, needs reapplying often.

Wears off unevenly, leaves you chasing the next dose.

Stays active longer so you get through the day.

💰 Total Cost

$10 to $40 per tube.

$30 to $200 per month after copays and deductibles.

$79 / month

Includes custom cream, physician consult & shipping.

Questions? Chat with us

One Cream. One Price. Zero Nonsense.

From appointments to disappointments, you've paid the price for pain relief that didn't deliver. Twinge is one cream that finally does.

🛒 Access

⏱️ Time to Relief

🧬 Personalization

⚡ Strength & Potency

⚠️ Side Effects

🎯 Targeting

⏳ Duration

💰 Total Cost

OTC Creams:

$10 to $40 per tube.
Oral Pills:

$30 to $200 per month after copays and deductibles.
Twinge Custom Cream:

$79 all in — custom cream, physician consult, fast shipping.

$79/month supply. No copays. No insurance. No hidden fees.

Arthritis & Joint Pain

Back Pain

Neuropathy

Foot & Heel Pain

Muscle Spasms & Strains

Sports & Overuse Injuries

Ready for Real Relief?

⌛ Limited Spots Remaining for September

Is Twinge Right for Your Pain?

Trusted by hundreds for lasting pain relief

Get a Custom Back Pain Relief Cream That Gets You Moving Again.

Stop letting back pain control your life. Get a prescription strength formula specifically designed for your back pain delivered to your door for one flat price.With Twinge Health, pain relief is simple. Here's what you get:

Real doctor reviews your back pain and prescribes your formula.

Targeted ingredients for your back. Not generic pain relief.

Skip pharmacy runs. Your cream ships free and fast with 2 day USPS Priority mail.

Your Back Betrays You Before You Even Start Your Day.

Get Doctor Prescribed Back Pain Relief Without Leaving Your Couch

Skip the waiting rooms and awkward positions in pharmacy lines. Get personalized, prescription strength back treatment delivered straight to your door.

Share Your Back Pain Story

Your Custom Formula is Created by a Pharmacist

Your Relief Gets Delivered

Every Ingredient Targets a Different Piece of Your Back Pain

We don't add fillers or fancy fragrances. Every component addresses a specific way back pain ruins your day.

Relieves deep muscle tension that locks up your spine.

Dr. Javed

Cools the fire of acute back flares instantly.

Dr. Javed

Silences shooting nerve pain down your legs.

Dr. Javed

Targets spine inflammation that causes morning stiffness.

Dr. Javed

Calms nerves that chronic back pain has sensitized.

Dr. Javed

Relaxes the muscle guarding that makes back pain worse.

Dr. Javed

Stops the spasm cycle that keeps you stuck.

Dr. Javed

Delivers relief deep into spinal tissue where it's needed.

Dr. Javed

Not Another Patch or Pill. This Is Real Back Relief.

Twinge targets the muscles, nerves, and inflammation causing your back pain with prescription-strength ingredients that work where you hurt most.

Beat your back to the punch.

Relief without the stomach pain.

Twinge penetrates deep. Inflammation retreats. Muscles unlock. You move freely.

Stops spasms before they stop you.

Built for your specific back pain.

Built by experts. Backed by real access.

They Called It a Game Changer. We Call It Personalized Relief.

These reviews come from people who thought they'd tried everything. Until they tried something made for their pain.

Matt

Relieved my chronic lower back pain in days

Amanda, 45

I can sit all day without discomfort again

Jeff, 80

Helps me stay active and avoid the cane

Theresa, 56

Finally, something that actually targets the pain

Paul, 52

Perfect for long days on the job site

LauraAnne, 59

Quick, easy relief for tension in my spine

Ani, 38

Soothing relief after long hours at my desk

Derek, 60

Works better than anything I've tried before

Yao, 47

Surprised by how well it worked for me

Frequently Asked Questions About Custom Back Pain Relief Creams.

From safety to shipping, here's everything you need to know about getting prescription-strength back pain cream made specifically for your spine and back muscles—delivered right to your door.

How is Twinge different from OTC back pain creams?

Do I need a prescription for Twinge back pain cream?

What types of back pain does Twinge help with?

Is Twinge covered by insurance?

Is it safe to use Twinge cream long term for back pain?

Can I use Twinge cream with my current back pain medications?

What if I'm allergic to certain ingredients?

Can I use Twinge cream with physical therapy or exercise?

How quickly do I see back pain improvements with Twinge?

What if the cream doesn't work for my back pain?

What if my back pain changes or moves to different areas?

Stop letting back pain control your life. Get a prescription strength formula specifically designed for your back pain delivered to your door for one flat price.

With Twinge Health, pain relief is simple. Here's what you get:

Twinge penetrates deep.
Inflammation retreats.
Muscles unlock.
You move freely.

Built by experts.
Backed by real access.